“the Evolution of Molecular Biology: a Scientific Revolution?”

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“The Evolution of Molecular Biology: A Scientific Revolution?” Indeed, the Sumerians and Babylonians had set the stage for the evolution of Molecular Biology back in around 8000 years ago. People selectively manipulated the organism like yeast, domesticated the livestock, cross-bred the crops for their survival. But it was not until the mid 18th century when Darwin discovered the laws of evolution that turned the mere descriptive, observational, and taxonomical biology into the functional biology that can quantify the observations and help us understand the life at molecular level. Every discovery made thereafter formed the basis for another discoveries. Scientists were approaching the reductionist approach to explore the genetic codes of nature and unravel the many basics of molecular and cellular processes. As everyone else, biochemists were also deducing the most complex entities of life by breaking into small individual steps and solving for each step. But the complexity of life indeed does not follow the footsteps of linear cause-effect mechanism and would not always give the result in reproducible fashion. One cannot predict the cause and effect by merely comparing with the results of less complex life, there is always chance of deviations and side effects in higher organisms. Hence the concept of holistic approach, which investigate the complex system as a whole and not by splitting it and recombining it as classic reductionist, appear and plays critical role in depicting the near causalities biochemical mechanisms in complex organisms. Together with Darwin theory of evolution, the Mendel theory of unit of heredity did an instant impact in the evolution of molecular biology that eventually set up the platform (indirectly) for its revolution. The discovery of nucleic acids 1944 by Avery et al, the discovery of double helix structure of DNA in 1953 by
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