There are many models of enzymes, such as the lock and key model, which explores the structure of the enzyme and its ability to bind with a substrate molecule which is specific and complementary. There is also the induced fit model which explored the ability of enzyme molecules to change shape slightly enabling it to fit and bind to substrate molecules which must be complementary and specific. The importance of enzyme and substrate molecules to fit together, is the formation of the products which may enable many vital reactions to occur within cells and organisms. Enzymes are in important in digestion and the replication of DNA. Within digestion lactose within milk is broken down by the enzyme lactase, without lactose having a complimentary specific shape to it lactase enzyme, some people are lactose intolerant.
The Importance of Shapes Fitting Together in Cells and Organisms Lots of molecules in cells and organisms fit together with other molecules that have complimentary shapes in order to work and serve their purpose. An example of a type of molecule that does this is enzymes. Enzymes are proteins that speed up metabolic reactions, from the digestion of food to the synthesis of DNA, and so are very important. One of two models that demonstrate how enzymes work is the ‘lock and key’ model, in which the active site of an enzyme has a complimentary shape to a specific substrate and they fit together perfectly (like a key in a lock, hence the name) to form an enzyme-substrate complex. The other model is the ‘induced fit’ model, which describes the formation of an enzyme-substrate complex as a result of the enzyme’s active site adapting its shape to fit with the substrate (almost like a glove) to allow for
If the amino acid sequence is altered in any way it will have repucutions on the secondary and tertiary structure because bonds will be formed in different locations and therefore a different 3D structure will be present, thus meaning shape of the active site will change in enzymes. so the substrate won’t fit into the active site and the enzyme will no longer be functional. Enzymes (proteins) act as biological catalysts so they speed up reactions. They’re soluble and often have roles in metabolism for example some digestive enzymes such as amylase, which breaks down starch into maltose. A proteins shape determines its function for example Collagen.
Another living property that living organisms possess is regulation. The environment outside of an organism may change drastically. However living organisms can adapt to such drastic changes by adjusting its internal environment therefore being able to coordinate internal functions, respond to stimuli, and cope with environmental stresses. All organisms grow and develop; another very important property that characterizes living things. Information carried by DNA controls the pattern of growth and development in all organisms.
| Vesicle | Storage in and out of the cell. | Cytoskeleton | The cytoskeleton plays a critical role in the determination of cell shape and serves as a scaffold for critical cellular enzymes and adhesion molecules. It provides structural integrity for the cell and regulates the function of many biochemical events that are critical to cellular function.
The breakdown of the membranes of these structures, affect the function of his heart cells because lysosomal enzymes which are normally bound safely inside vesicles will digest the plasma membranes and the membranes of the organelles. D.) Predisposition means that Joseph inherited vascular disease. Dna is in the nucleus of the cell. We need DNA to replicate or repair our cells. Also, cytosol is the site of chemical reactions needed to maintain cell structures and allow cell growth.
How would the breakdown of the membranes of these structures affect the function of Joseph’s heart cells? All intracellular organelles have membranes as part of their structure except ribosomes. The breakdown of these membranes affect the function of the heart because the lack of ATP has affected the plasma membrane pumps and stopped the moving of the ATPase calcium from the cytosol to the endoplasmic reticulum of the cardiac muscle. As the calcium level rice the protease spill into the interior of the cell which attacks the cytoskeleton, causing enzymes to eat away at the membranes. Queston D: Two important pieces of information-the instructions of Joseph’s body needs to repair itself and his predisposition for vascular disease- are both contained within the cell on which structures?
2. Genes carry important information for the production of all proteins through a process known as gene expression. Transcription occurs first, this is where the information stored in a gene’s DNA is transmitted to RNA in the cell nucleus. Messenger RNA carries this information from the DNA out of the nucleus into the cytoplasm. The second step, translation then occurs and this takes place in the cytoplasm.
Enzyme has an active site in a specific shape because of its tertiary structure. Enzyme works for binding with substance of a specific shape that fits in it and break down the substance. Enzymes denature due to various factors. The temperature, PH level, and the concentration of the substance influence enzyme activities. When these factors vary, enzymes may change in shape so it will not be able to bond to the specific substance anymore.
In this case, the most effective factor is the reactant concentration, where the reactant is the enzyme. Enzymes are composed of proteins; therefore their characteristics reflect the properties of proteins which are extremely interesting properties that make enzymes little chemical-reaction machines. The purpose of an enzyme in a cell is to allow the cell to carry out chemical reactions very quickly. These reactions allow the cell to build things or take things apart as needed. This is how a cell grows and reproduces.