Inheritance Of Marfan Syndrome

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Abstract Inheritance of Marfan syndrome: Age of onset associated with Marfan syndrome, gene locus and mutations, disorders attributed with Marfan syndrome, and the common treatments for those affected with Marfan syndrome. MARFAN SYNDROME 3 Marfan syndrome Marfan syndrome is a familiar heritable disorder that affects the fibrous connective tissue with remarkable pleiotropism and clinical variability. (McKusick, 1991) The cardinal signs of Marfan syndrome are discernible in the eye, causing near sightedness from an increased curve of the retina related to the changes that occur with the connective tissue in the globe of the eye. As a result there is an increased risk for retinal detachment, and early cataract formation. The skeletal and connective tissue system include; bone overgrowth and loose joints this causes the arms and legs to become abnormally long and thin. An overgrowth of the ribs can cause the chest bone to bend inward or push outward causing…show more content…
Supplemental medications such as beta blockers are recommend delaying, but not significantly found to prevent the potential need for aortic surgery. Angiotensin II receptor blockers have been known to deliver additional protection of the aorta from dilatation. Aerobic exercise is recommended to reduce complications associated with Marfan syndrome. However, participation in contact and competitive sports are discouraged as this can increase the risk for injury related to fibrous connective tissue and skeletal system peril. (McKusick,

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