Blood Vessels Essay

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BME 5390 Outlook on Development of Tissue Engineered Blood Vessels May 16, 2014 Prepared and Submitted: Barbara Varsonofieva Zachary Goldblatt Kahini Vaid Nojoud Mohammad AL Fayez Andy Huang Table of Contents Abstract | ………………………………………………………………………….1 | Introduction | .…………………………………………………………………………1 | Vascular Grafts | …………………………………………………………….…………… | Stem Cells | .………………………………………………………………………… | Vascularization | ………………………………………………………...……………….. | ScaffoldBiodegradableDecellularizedSynthetic/NaturalSelf-assemblyProtein Networks | ………………………………………………………...………………………………………………………………………...………………………………………………………………………...………………………………………………………………………...………………………………………………………………………...……………… | Scaffold-freeSelf-assemblyBioprinting | ……………………………………………………...…………………………………………………………………………...……………… | Conclusion | ……………………………………………………...………………… | Bibliography | ……………………………………………………...………………… | Introduction The basic function of blood vessels is to transport blood from the heart to all the tissues in the body and back to the heart. Apart from blood transport, they are also capable of carrying fluids throughout the body and subsequently allowing the exchange of materials with blood, and vasoconstriction/ vasodilation to alter blood flow. [6k] This being the functional properties, blood vessels can vary from one another in their structural and biochemical composition of the walls which are dependents for the strength and deformative properties of blood vessels. [7k] The main components/ layers that make up blood vessels are tunica intima, tunica media and tunica adventitia. [1k] Since, there are a number of layers that make up the vessels walls, they exhibit inelastic behaviour for instance, length- tension and pressure- diameter hysteresis, stress relaxation, and creep. Inspite of these irregularities, the vessels are capable of maintaining stability
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