Creutzfeldt-Jakob Disease Essay

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Creutzfeldt-Jakob disease, otherwise known as CJD, is a form of brain damage that leads to a rapid decrease of mental function and movement. CJD has been thought to be caused by a protein called prion. Prions cause normal proteins to fold abnormally, thus causing other proteins functions to then be affected. There are several types of Creutzfeldt-Jakob disease which are all very rare. CJD can be grouped in three categories: sporadic disease, familial cases, and iatrogenic cases. The two different forms of CJD vary in multiple ways in that of the symptoms, treatment options, as well as how the disease is prevented. The pathogen that causes this deadly illness is a small protein called prion. This prion is a small proteinaceous infectious disease-causing agent that is the smallest infectious particle. Prions are neither fungal nor viral and they contain no genetic material, but they have been held responsible for a number of degenerative brain diseases including CJD. The harmless and infectious forms of prion protein are nearly identical making it nearly impossible to tell the difference, but the infectious prion takes a folded shape compared to the normal protein. For many reasons still unknown this prion, when altered, can destroy nervous system tissues like the brain and the spinal cord. Creutzfeldt-Jakob disease and its variants belong to a broad group of human and animal diseases known as transmissible spongiform encephalopathies or TSEs. The name is derived from the spongy holes that are only visible under a microscope that develop in the affected brain tissue. The risk of getting Creutzfeldt-Jakob disease is very low and usually affects people over the age of 60. It cannot be transmitted through coughing, sneezing, touching, or sexual contact. There are three ways that you can get Creutzfeldt-Jakob disease. You can get it spontaneously, and most

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