Research Paper Outline For Addison's Disease

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Addison’s Disease Definition: is a rare and chronic endocrine system disorder in which the adrenal glands do not produce sufficient steroid hormones. It is characterised by a number of relatively nonspecific symptoms, such as abdominal pain and weakness, but under certain circumstances, these may progress to Addisonian crisis, a severe illness which may include very low blood pressure and coma. Risk Factors: * have cancer * take coagulants (blood thinners) * have chronic infections like tuberculosis * had surgery to remove any part of your adrenal gland * have an autoimmune disease, like type 1 diabetes or Graves’ disease Causes: Addison's disease results when your adrenal glands are damaged, producing insufficient…show more content…
The pituitary gland makes a hormone called adrenocorticotropic hormone (ACTH), which stimulates the adrenal cortex to produce its hormones. Inadequate production of ACTH can lead to insufficient production of hormones normally produced by your adrenal glands, even though your adrenal glands aren't damaged. Doctors call this condition secondary adrenal insufficiency. Another more common cause of secondary adrenal insufficiency occurs when people who take corticosteroids for treatment of chronic conditions, such as asthma or arthritis, abruptly stop taking the corticosteroids. Addisonian crisis: If you have untreated Addison's disease, an addisonian crisis may be provoked by physical stress, such as an injury, infection or illness. Signs and Symptoms: * Muscle weakness and fatigue * Weight loss and decreased appetite * Darkening of your skin (hyperpigmentation) * Low blood pressure, even fainting * Salt

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