Biochem Exam 3 Study Answers

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Biochem Exam 3 Study Guide * What will be the product of pancreatic lipase?? Chapter 8 - Lipids How the fatty acids are denoted according to IUPAC nomenclature rules? # carbons: # double bonds … 18:2, cisΔ9,12 linoleic acid. Double bonds in fatty acids usually have the cis configuration. Each cis double bond causes a kink in the chain, or a bent tail. Most naturally occurring fatty acids have an even number of carbon atoms—12-24. What are the unique structural features of fatty acids? Amphipathic, having a non-polar end and a polar end. Fatty acids consist of a long hydrocarbon "tail“, which is hydrophobic due to nonpolar C-H bonds, attached to a hydrophilic "head" consisting of a carboxyl group. How does lipid…show more content…
The exterior surface of the plasma membrane can contain carbohydrates. How are the peripheral proteins attached to membrane? Peripheral (extrinsic) proteins are associated with the surface of the bilayer surface via ionic interactions (electrostatic) and H bonds. They do not extend into the hydrophobic interior and can be removed by agents that disrupt ionic interactions and H bonds, such as high salt concentrations, urea, or extremes of pH. How do proteins associate with cell membrane? They associate as either peripheral or integral proteins. Associating as peripheral or integral depends on whether they are hydrophobic and can attach into the bilayer or hydrophilic and must stay on the outside of the bilayer via ionic interactions or H bonds. Integral proteins usually must be removed with detergents. How does the presence of cholesterol affect lipid…show more content…
Cholesterol also makes the membrane less fluid by restraining the movement of phospholipids and lowers the temperature required to solidify the membrane. Complete depletion of cholesterol and sphingolipids results in cell death as their presence allows permeability to small molecules such as ions, glucose, and water. How does temperature affect lipid membrane? A membrane remains fluid as the temperature decreases, until it solidifies once it hits a critical temperature. The temperature at which a membrane solidifies depends on its fatty acid composition. A membrane rich in unsaturated tails will remain fluid to a lower temperature. How are the proteins attached to cell membrane via lipids? They are attached through lipid-anchored cell membrane proteins. They are attached through myristoylation, palmitoylation, or isoprenylation. What are the lipid rafts? How do they form and what is their function? A lipid raft is a membrane domain which is enriched in sphingolipids and cholesterol (liquid ordered phase). Rafts are postulated to grow by accumulation of cholesterol, sphingolipids, and GPI-anchored proteins. Lipid rafts can assist in cellular signaling. What is meant by asymmetric structure of biological
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