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These changes may alter the following: ›hormone production and secretion ›hormone metabolism (how quickly hormones are broken down and leave the body) ›hormone levels circulating in blood ›target cell or target tissue response to hormones ›rhythms in the body, such as the menstrual cycle For example, increasing age is thought to be related to the development of type 2 diabetes, especially in people who might be at risk for this disorder. The aging process affects nearly every gland. With increasing age, the pituitary gland can become smaller and may not work as well. For example, production of growth hormone might decrease. Decreased growth hormone levels in older people might lead to problems such as decreased lean muscle, decreased heart function, and osteoporosis.
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