Lymphatic and Immune Systems

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Lymphatic and Immune Systems Lymphatic and Immune Systems 1. Non-specific immunity. * It protects against a broad range of pathogens by using mechanisms such as external barriers, phagocytosis, antimicrobial proteins, natural killer cells, inflammation and fever. * Its first line of defense is surface barriers like skin and mucous membranes that keep most of the pathogens we come across at bay. a. Skin, which represents a physical barrier to most microorganisms and their enzymes and toxins. b. Mucosa. Mucous membranes line all body cavities open to the exterior and function as an additional barrier. * Its second line of defense is internal and consists of cells and chemicals. It occurs if a pathogen pierces through the first line of defense. a. Phagocytes, which confronts microorganisms that breach the external barriers. They include macrophages, neutrophils, and eosinophils. b. Natural killer cells, which helps monitor the body. They kill cancer cells and viral-infected cells. c. Inflammation, which occurs when the body tissues are injured. d. Antimicrobial proteins, which enhance innate defenses by attacking microorganisms. e. Interferons, which help protect surrounding healthy cells. And more. Specific immunity * It is specific toward one type of pathogen. It has a different reaction determined by the factors such as first time exposure or second time exposure. The two mechanisms of specific immunity are T-Lymphocytes (cellular) and B-Lymphocytes (humoral). * Antibodies are proteins secreted by plasma cells in response to an antigen that are capable of binding to that antigen. * Cell mediated immune response is immunity conferred by activated T cells, which directly kill infected or cancerous body cells or foreign grafts and release chemicals that regulate the immune system. Contrast to

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