Lorenzo's Oil

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Name: Mary Grace H. Tizon Section: IV – Einstein January 26, 2011 Movie Review: Lorenzo’s Oil I. Summary of the story (write the summary as if you are telling the story) The story was based on a true story of Augusto and Michaela Odone, two parents in a relentless search for a cure for their son Lorenzo’s adrenoleukodystrophy (ALD). Failing to find a doctor capable of treating their young son Lorenzo’s rare disease, Augusto and Michaela Odone sought their own cure. In their quest, the Odones clashed with doctors, scientist, and support groups, who were skeptical that anything could be done about Adrenoleukodystrophy (ALD), much less by laypeople. They persisted, setting up camp in medical libraries, reviewing animal experiments, badgering researchers, questioning top doctors all over the world, and even organizing an international symposium about the disease. Despite dead ends of research,the horror of watching their son’s health decline, and being surrounded by skeptics, they persisted until they finally hit upon a theraphy involving adding a certain kind of oil, both isolated from rapeseed oil and olive oil to their son’s diet. They contacted over 100 firms around the world until they found an elderly British chemist (Don Suddaby) working for Croda International who was willing to take on the challenge of distilling the proper formula. It proved successful in normalizing the accumulation of the very long chain fatty acids in the brain that had been causing their son’s steady decline, thereby halting the progression of the disease. There was still a great deal of neurological damage remaining which could not be reversed until new treatments were found to regenerate the myelin sheath (a lipid insulator) around the nerves. The film ends with Lorenzo at age of 14 showing definite improvement. The end credits of the film note that Lorenzo

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