Causes of Malaria

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1.1BACKGROUND Malaria, a mosquito-borne, protozoal disease, is older than recorded history, and probably plagued prehistoric man (Lambert, 2002). The first record of a treatment for the disease dates from 1600 A.D. in Peru, and utilized the quinine-rich bark of the Cinchona tree.(Lambert, 2002). Scientifically, it is not a newly described disease. The French physician Charles Louis Alphonse Laveran first identified the parasite under the microscope in 1880. Ronald Ross and Giovanni Grassi recognized the mosquito as the malaria vector in 1897 (Good, 2001). However, despite enormous and diverse efforts to control this disease, malaria is among the top three most deadly communicable diseases and the most deadly tropical parasitic disease today (Sachs and Malaney, 2002). According to the World Malaria Report 2010, there were 225 million cases of malaria and an estimated 781 000 deaths in 2009, a decrease from 233 million cases and 985 000 deaths in 2000. Most deaths occur among children living in Africa where a child dies every 45 seconds of malaria and the disease accounts for approximately 20% of all childhood deaths (WHO 2010). Malaria is a major cause of illness and death in Ghana, particularly among children and pregnant women in Ghana. In 2006, malaria accounted for 38.6% of all outpatient illnesses and 36.9% of all admissions (MOH, 2009). Malaria prevalence per thousand populations was 171 and 2,835 malaria-attributable deaths (all ages) representing 19% of all deaths were recorded. Infection rates are high in children peaking at more than 80% in those aged 5 – 9 years and falling to low levels in adults (MOH, 2009). Malaria infection during pregnancy causes maternal anaemia and placental parasitemia both of which are responsible for miscarriages and low birth weight babies among pregnant women. 13.7% of all admissions of pregnant women in 2006 were as a

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