Vitiligo Research Paper

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Cameron Hilliard Coach Bell Research paper 17 September 2012 Vitiligo Vitiligo is a skin condition in which there is a loss of brown color (pigment) from areas of skin, resulting in irregular white patches that feel like normal skin. Vitiligo occurs when the cells that produce melanin die or no longer form melanin. These areas of skin have a darker border and the edges are well defined but irregular. It most often affects the face, elbows, knees, hands, feet, and genitals. It also affects both sides of the body evenly. Vitiligo is more noticeable in darker skinned people because of the contrast of the white patches against dark skin. The patches of skin are smooth like the rest of the skin around it. Vitiligo is a multifactorial, polygenic disorder with a complex pathogenesis. That means it is hard to find out where or who it came from. Mainly it has to be passed down in the genes of your family. It is also related to genetic and non genetic factors. Vitiligo occurs when melanin-forming cells (melanocytes) fail to produce…show more content…
Steroids have been reported anecdotally to achieve success when given in pulse doses or low doses to minimize adverse effects. The benefits versus the toxicity of this therapy must be weighed carefully. More research is necessary to establish the safety and effectiveness of this therapy for vitiligo. A topical steroid preparation is often chosen first to treat localized vitiligo because it is easy and convenient for both doctors and patients to maintain the treatment. The results of therapy have been reported as moderately successful, particularly in patients with localized vitiligo and/or an inflammatory component to their vitiligo, even if the inflammation is subclinical. In general, intralesional corticosteroids should be avoided because of the pain associated with injection and the risk of cutaneous
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