Some of the more common complications associated with the disease are bowel obstruction, ulcers, and fistulas. Bowel obstruction is the most common and results from the thickening of the intestinal wall with swelling and scar tissue, narrowing the passage. The narrowing of the intestines blocks flow of digested material through the affected area. In severe conditions surgery is needed to remove the dead and damaged tissue of the bowel. Chronic inflammation that accompanies this disease can lead to the formation of ulcers.
Crohn’s disease is an ongoing inflammation bowel disease of the digestive tract, also referred to as the gastrointestinal (GI) tract that can cause ulcerations which is breaks in the lining of the small and large intestines. Crohn’s disease is named after the physician who described the disease in 1932 (www.gicare.com). Crohn’s disease can affect any area of the GI tract, from the mouth to the anus, but it most commonly affects the lower part of the small intestine, called the ileum. The swelling extends deep into the lining of the affected organ. The swelling can cause pain and can make the intestines empty frequently, resulting in diarrhea.
A trypsinogen test is also ordered when children or adults present with symptoms suggesting cystic fibrosis and pancreatic dysfunction such as persistent diarrhea, foul-smelling, bulky greasy stools, malnutrition, and vitamin deficiency. Trypsinogen testing is non-diagnostic; there are a fair number of false positives and problems other than cystic fibrosis and pancreatic dysfunction that can cause a positive IRT. An elevated level must be followed with other testing. When diagnosing cystic fibrosis, this may include another IRT in a month, CF gene mutation testing, and/or sweat chloride testing. If an IRT level is elevated, an infant may have cystic fibrosis; an infant or adult may have abnormal pancreatic enzyme production, pancreatitis, or pancreatic cancer; or the elevated IRT may be a false positive.
During the active phase the most common signs and symptoms include diarrhea, abdominal cramping, rectal bleeding, ulcers, reduced appetite, and weight loss. Other signs and symptoms include fever, fatigue, arthritis, eye inflammation, skin disorders and inflammation of liver or bile ducts. Diarrhea is the most common symptom due to the inflammation of the intestines that causes them to secrete a large amount of fluid and salt. Since the colon cannot absorb this extra fluid, the person develops severe diarrhea. Abdominal pain and abdominal cramping is caused the inflammation of the walls and eventually thickens the walls with scar tissue and leads to cramping.
Genital herpes causes painful genital ulcers in many adults that can be severe and persistent in persons with suppressed immune systems, such as HIV-infected persons. Both HSV-1 and HSV-2 can also cause rare but serious complications such as blindness, encephalitis (inflammation of the brain), and aseptic meningitis (inflammation of the linings of the brain). Development of extragenital lesions in the buttocks, groin, thigh, finger, and eye may occur during the course of infection. 8 Some persons who contract genital herpes have concerns about how it will impact their overall health, sex life, and relationships. There can be can be considerable embarrassment, shame, and stigma associated with a herpes diagnosis and this can substantially interfere with a patient’s relationships.
The following are the most common symptoms in patients with Cystic Fibrosis: very salty tasting skin, persistent cough with phlegm, frequent lung infections, wheezing and shortness of breath, poor growth despite a healthy appetite, frequent greasy, bulky stools or difficulty in bowel movements. In addition to these symptoms, there are other medical issues such as sinusitis, nasal polyps, Pneumothorax (a collapsed lung due to intense coughing), Hemoptysis (coughing up blood), liver disease, gallstones, diabetes, and clubbing of the fingers and toes. (A condition marked by extremely thickened fingertips and toes due to decreased oxygen in the
Some of the common triggers for sickle cell crisis are fever, dehydration, stress, infection, hypoxia, bleeding, cold exposure, and drug and alcohol use. The immune system for people with sickle cell anemia is weakened which increases the likelihood of infection from flu viruses and bacteria which could lead to a fever. There are four different types of crises that are label based on the area of the body affected. They are bone, abdominal, chest, and joint crisis. During a sickle cell crisis, the pregnant person may present with severe unrelenting pain that is accompanied by nausea, vomiting, coughing up blood, diarrhea, or decreased range of motion of the affect extremity.
Here is how Cystic Fibrosis affects the different body systems and the signs and symptoms that accompany these. Hepatobiliary System: (the liver and the secretions from the liver) malfunctioning secretion/production can cause liver disease and gallstones, leading to pain and jaundice (yellowing of the skin) Liver disease (liver cirrhosis): complications include a fatty liver, which usually doesn't create problems except in infants; focal biliary fibrosis, which causes the liver to first enlarge and then shrink like a typical cirrhotic liver and is caused by blockage of the bile ducts, which leads to inflammation, leading to fibrosis; and then development of cholesterol gallstones. Sweat Gland
Crohn’s Disease Rosa Capela Kaplan University: SC131 January 21, 2015 What is Crohn’s Disease? Crohn’s Disease is an inflammatory bowel disease, causing the lining of your digestive tract to flame up. When the disease is active many symptoms can be caused, including abdominal pain, severe diarrhea, fatigue (extreme tiredness), weight loss, and malnutrition (lack of proper nutrition). Inflammation of the skin eyes and joints, inflammation of the liver of bile ducts and delayed growth or sexual development, in children are also signs and symptoms of Crohn’s Disease. Scientists believe Crohn’s Disease is caused by a combination of these 3 factors: Immune system problems, genetics, and environmental factors.