Obesity Essay

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What is obesity? Obesity is a chronic disease that is characterized as a person who has an increased amount of body fat. (Penatti, 1547-1553). When someone is 20% or more over their ideal body weight in correlation to their height, they are considered obese. Obesity has also been connected to being the cause of some serious health risks for example, hypertension, hyperglycemia, hyperlipidemia, and non-insulin-dependent diabetes mellitus and also, death (Grilo, 1991). There are many things that can cause obesity. There are, genetic factors that cause obesity and also, environmental factors are linked to causing obesity. In the end, both genetics and environmental factors can be responsible for causing of obesity. One thing that can possibly cause obesity is someone’s genetics, but there are not many proven genetic causes of obesity. A genetic cause of obesity can be linked to the brain-derived neurotropic factor (BDNF), which is related to eating behavior and weight regulation (Ooi, 2012). In rats, the central infusion of BDNF resulted in loss of appetite and both weight loss or weight gain and the mice that had reduced BDNF became obese but it was “reversible with BDNF infusion into the third ventricle”. “Infusion of BDNF into the ventromedial hypothalamus and paraventricular nucleus” resulted in a decrease in food intake and weight loss (Ooi, 2012). The relationship between serum BDNF levels, abnormal eating behaviors, and weight regulation has been studied. In adults, obese patients had increased serum BDNF levels and patients with anorexia and bulimia nervosa the serum BDNF levels were decreased (Ooi, 2012). Monogenic Obesity is when a mutation occurs in a single gene, called monogenic mutations. These mutations have been discovered in genes that play roles in appetite control, food intake, and energy homeostasis. Especially in genes that, “code for the hormone

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