O Levels Biology Cell Division

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Chai Hao Wei (17) 311 Biology Chapter 18: Cell Division Growth: permanent increase in size accompanied by cell division and differentiation Mitosis: Cell division during growth * Growth in plants restricted to growing points: shoot and root tips A nuclear division such that the daughter nuclei produced contain the same number of chromosomes as the parent nucleus * Non-dividing stage of a cell (still absorb nutrients and build protoplasm) * Chromosomes appear as long thin threads called chromatin which cannot be distinguished individually * Centrioles in animal cells divide and chromatin threads replicate Interphase nuclear envelope centrioles chromatin cytoplasm Zygote cells need to be genetically stable for the embryo to develop normally. Replication of Chromatin Threads 1. Two identical chromatin threads produced coil and shorten to become chromosomes 2. Each chromosome consists of two identical DNA molecules called sister chromatids. 3. Chromatids joined at a point called centromere. Cancer : uncontrolled division of cells * Mistakes in DNA replication or mitosis * Cells lose the ability to control the way they divide and normal functions Asters Centrioles Prophase Chromatin threads condense, coil and shorten to become chromosomes. Each chromosome consists of two sister chromatids attached at the centromere. The chromosomes are now visible under a microscope. sister chromatids (one chromosome) centromere Late prophase: * Nuclear Envelope disintegrates * Spindle forms with spindle fibres extending from one pole of the cell to the other In animal cells: * Structures called asters(made up of microtubules) form around centrioles * Centrioles move apart to opposite ends of cells Microtubules are hollow protein structures found in cytoplasm of cells.

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