Myasthenia Gravis Essay

934 WordsJul 24, 20124 Pages
Myasthenia Gravis Myasthenia Gravis is one of many neuromuscular disorders. It literally means “grave muscle weakness.” This chronic autoimmune neuromuscular disorder affects every “2 per 1,000,000 people per year.” “ The onset is 28 years for female and 42 years for males.” (Aashit K Shah M. , 2011) Muscle weakness occurs and increases with physical activity and usually improves after resting. This muscle weakness is caused by an interruption of the transmission of nerve impulses to the muscles. We can say it’s just the wrong communication to the muscle, preventing voluntary muscles from contracting. Also, “antibodies block receptors for acetylcholine at the neuromuscular junction.” (Aashit K Shah M. , 2011) This neuromuscular junction is a space between nerve endings and muscle fiber. The reason MG is called an autoimmune disease is because there are not enough antibodies being produced, causing muscle weakness. Adults that have been diagnosed with MG have a large and abnormal thymus gland; this gland is located in the chest below the breastbone. The thymus gland develops our immune system. Some people develop tumors in the gland, which are usually benign. If a tumor is found surgery can be done to remove the thymus gland Myasthenia Gravis affects many parts of our bodies system. The axial skeletal system is involved because the brain is enclosed in this area, and MG affects the cerebellum, the part of the brain that coordinates action. The maxilla, mandible, and palatine parts of the skull because they all involve chewing. MG causes chewing and swallowing to be difficult, also the nasal bone because aspiration can happen in more severe cases. The Appendicular skeletal area is also affected because the arms and legs are involved because of the muscle weakness. All in all, one can say any part of the skeletal system can be

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