Lupus Research Paper Free

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Lupus, what is it and how it affects you. Systemic Lupus Erythematosus often abbreviated to SLE or lupus is a chronic autoimmune connective tissue disease that can affect any part of the body. As occurs in other autoimmune diseases, the immune system attacks the body’s cells and tissue, resulting in inflammation and tissue damage. SLE most often harms the heart, joints, skin, lungs, blood vessels, liver, kidneys, and nervous system. The course of the disease is unpredictable, with periods of illness (called flares) alternating with remissions. The disease occurs nine times more often in women than in men, especially between the ages of 15 and 30, and is more common in those of non-European descent. SLE is treatable through addressing…show more content…
There are, however, a number of environmental triggers and a number of genetic susceptibilities. Genetics The first mechanism may arise genetically. Research indicates that SLE may have a genetic link. SLE does run in families, but no single casual gene has been identified. Instead, multiple genes appear to influence a person’s chance of developing lupus when triggered by environmental factors. Environmental triggers The second mechanism may be due to environmental factors. These factors may not only exacerbate existing SLE conditions but also trigger the initial onset. These factors include certain medications (such as some antidepressants and antibiotics), extreme stress, exposure to sunlight, hormones, and infections. Ultra-violet (UV) radiation has been shown to trigger the photosensitive lupus rash and some evidence suggests that UV light might be capable of altering the structure of the DNA, leading to the creation of autoantibodies. Sex hormones such as estrogen play an important role in the occurrence of SLE and it is observed that during reproductive years, the frequency of SLE is 10 times greater in females than in…show more content…
Discoid rash: red scaly patches on skin that cause scarring. The acronym to remember the 11 symptoms is SOAP BRAIN MD. Some people, especially those with antiphospholipid syndrome, may have SLE without four criteria, and also SLE may present with features other those listed in the criteria. Treatment Being a chronic disease with no known cure, the treatment of SLE is symptomatic. In essence, this involves preventing flares and reducing their severity and duration when they occur. Medications Due to the variety of symptoms and organ system involvement with SLE, its severity in an individual must be assessed in order to successfully treat SLE. Mild or remittent disease can sometimes be safely left untreated. If required, non steroidal anti-inflammatory drugs and antimalarials may be used. Disease-modifying antirheumatic

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