Lmyphatic & Immune Systems

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Module 07 Written Assignment Questions 1. Compare and contrast non-specific immunity and specific immunity. Be sure to discuss first and second lines of defense as well as cell-mediated and antibody mediated immunity. Non-specific immunity and specific immunity are responses that take place within the body when a threat is presented and needs to be fought off. Through the use of white blood cells, these two forms of immunity are able to attack harmful pathogens triggering inflammation and/or fever. When a pathogen attempts to gain access to our bodies, they must penetrate the first line of defense consisting of external barriers including the skin and mucus membranes. Should the threat be successful at passing the first line of defense, non-specific immunity becomes active and launches several mechanisms geared at repelling it. Nonspecific immunity, also known as innate immunity, are responses aimed at a broad range of attackers rather than one specific pathogen. The term “innate” is used as these mechanisms are present at birth which allows the body to defend against pathogens it has yet to experience. The last line of defense is known as specific immunity which is the body’s ability to retain memory of a previous invader allowing it to quickly identify it and initiate an appropriate response should it be exposed again in the future. (Thompson, 2013, p. 314) Specific immunity employs two essential mechanisms to destroy pathogens both inside and outside of cells. These are known as cell-mediated and antibody mediated immunity. Cell-mediated immunity aims to destroy either foreign or host cells that have become infected by a pathogen while antibody mediated immunity sends out antibodies to “mark” pathogens outside of the host cell(s) for later destruction. (Thompson, 2013, p. 319) 2. Describe the events that occur during the inflammatory response. Explain the
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