Hodgkins Lymphoma Cancer Essay

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Hodgkin’s lymphoma, formerly known as Hodgkin’s disease, is a potentially curable lymphoma with distinct biologic behavior, and clinical characteristics. Thomas Hodgkin first described the disorder in 1832; in the 20th century, it was renamed to Hodgkin’s Lymphoma when there was realization that the disease was a lymphoid malignancy. Hodgkin’s Lymphoma is a cancer of the lymphatic system. Hodgkin's lymphoma is one of two common types of cancers of the lymphatic system. The other type, non-Hodgkin's lymphoma and is far more common. Hodgkin’s Lymphoma is originated in the white blood cells, also known as lymphocytes. The etiology of Hodgkin’s Lymphoma is unknown; doctors do know that it normally occurs when the B cell, which is an infection-fighting cell, develops a mutation in its DNA. The mutation causes the cells to rapidly divide and continue living, therefore causing a large number of oversized abnormal B cells to accumulate and crowd out the healthy cells. The abnormal B cells may accumulate in the lymph nodes, spleen and lymphatic tissue, causing painless and progressive swelling. Eventually, Hodgkin's lymphoma can spread from the lymph nodes throughout the body. Because the lymphatic system is part of the immune system, when Hodgkin’s Lymphoma begins to progress it compromises the body’s ability to fight infection. Various types of Hodgkin’s Lymphoma exist. The type is based on the types of cells involved in the disease and their behavior. The type also determines the treatment options. The types of Hodgkin’s Lymphoma are: Classical Hodgkin’s Lymphoma Lymphocyte-Predominant Hodgkin’s Lymphoma Classical Hodgkin's lymphoma is the most common type of this disease, and it can be broken down further into subtypes. Lymphocyte-Predominant Hodgkin’s Lymphoma is a rare type of this disease and involves large, abnormal cells that are sometimes called

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