Grignard Reaction Lab Report

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Emmanuel Omolola Orgo Chem 2 Sec #1 (4-6pm) October 8, 2012 Grignard Reaction with a Ketone: Triphenylmethanol Purpose: The purpose of this exeperiment was to synthesize tripheymethol from a Grignard reagent, phenylmagnesium, bromide, bromobenzene, and benzophenone. Since the Grignard reagent is such a strong nucleophile and base, it is important to prevent water and other protic materials from interfering with Grignard reagent are developed. The experiment involved two reactions. First the Grignard reagent, phenylmagnesiumbromide, was synthesised from bromobenzene, magnesium and diethyl ether. Once produced, the Grignard reagent was then used to synthesise triphenylmethanol by reacting it with benzophenone. Reaction Scheme: Theory Reaction Mechanism The halide can be Iodide, chloride, or bromide, but fluoride is too unreactive form Magnesium to be used.…show more content…
We used .112 moles of bromobenzene, and .0103mole of magnesium moles of Methyl benzoate was the limiting reagent in the experiment. In calculating the theoretical yields. We used the limiting reagent multiplied by the molecular weight of the product. The initiation of the Grignard reaction began after about ten minutes of gentle heating was applied to thereaction flask containing the crushed magnesium turnings and first portion of the bromobenzene/anhydrous diethyl ether solution. This initiation was evident by cloudiness and graying of solution as well as the evolution of bubbles off the surface of the metal. The flask became warmer anddid not need additional heat because of the exothermic nature of the reaction. The remaining bromobenzene solution was added dropwise at a rate that kept the contents in the flask gently boiling. Asthe magnesium disintegrated, the contents turned from gray to dark brown to brownish red and finally

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