Gout Essay

563 WordsAug 8, 20123 Pages
GOUT Marcus Bozeman National College Robin Smith – COM151 2-29-12 Gout Gout is the oldest known form arthritis that causes severe pain and swelling in the joints. Like most diseases it has a history, symptoms, can be diagnosed, treated and managed. Gout was first identified by the Egyptians in 2640 BC and later recognized as by the Hippocrates in the fifth century BC, who referred to it as `the unwalkable disease`. Gout was later named Podarga, a Greek word meaning “foot pain”. Throughout time gout was considered the “disease of the Kings” which was another name for gout, because it was believed that the consumption of excessive alcohol and a rich diet. During the twentieth century there has been many technological advances. Researchers are constantly seeking a remedy although there are several pharmaceutical presently used for this historical ailment. Gout is a common disease which is caused by the buildup of uric acid in the joints, tissue deposition of uric acid crystals, and could cause joint destruction if left untreated. Uric acid is a byproduct of purine metabolism. Humans remove uric acid primarily by renal excretion. Normally, uric acid dissolves in your blood and passes through your kidney into your urine. But sometimes your body either produces too much uric acid or your kidneys excrete too little uric acid. When this happens, uric acid can build up, forming sharp, needle-like urate crystals in a joint or surrounding tissue that cause pain, inflammation and swelling. The pain or swelling at first would appear minimal but will lead to serve pain and make it very difficult to move the joint. The lightless touch would aggravate it. Over time gout attacks recur more and more frequently and affect more joints. Eventually, stone-like deposits known as tophi may build up in the joints, ligaments and tendons, leading to permanent joint deformity.

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