A binding material can be separated by dissolving the tablet in ether since three active ingredients are soluble. Then, aqueous K2HPO4 and KOH are used to extract the ether solution with the conjugate base of the Aspirin layer and the conjugate base of the Acetaminophen, respectively. The caffeine can be isolated from the left over layer by evaporating the ether. Two separated solutions form solid by acidifying with HCl and the solid residue can be collected by vacuum filtration. According to the Revell's lab experiment, aspirin, acetaminophen, caffeine recoveries are 60% or higher, <10% and <5%, respectively.
* What is this substance This substance is iodide Confidence Report The aim of extraction, is to separate a part of raw material, using a solvent such as water with heat. A tincture of iodine is a common medicine sold in many pharmacies, used as an antiseptic on cuts of the skin. The objective of the seaweed lab, is to produce a tincture of iodine by extracting Iodide and other components (seen when a mixture of iodine is present), from seaweed. We
It displays the peak area on the Y axis and the concentration on the X axis. 9 Conclusion: The main purpose of this lab was to find the main ingredients in an Excedrin tablet as well as how much of each ingredient is in the tablet. Two different techniques were used to help develop the ingredients. The two techniques used were extraction and HPLC. It was concluded that Excedrin tablets consist of acetaminophen, aspirin, and caffeine.
An example of use is cleaning compounds of impurities, where different solvents work as a molecular filter that interacts differentially with compound and impurities respectively. In the end of the process, impurities become physically separated from the now pure compound, facilitating further transferring and further repurification / extraction if needed. MATERIALS AND METHODS Acetanilide tert-butyl methyl ether p-tert-butylphenol p-toluic acid 0.5M NaHCO3 3M HCL 0.5M NaOH NaSO4 anhydrous Separatory Funnel Buchner filter paper Sand Bath Microspatula Disposable Pipet heated plate boiling chips support stand Pasteur pipets with latex bulb test tubes (2) utility clamp watch glasses weighing paper melting pint capillary tubes thermometer EXTRACTION •Dissolve acetanilide, p-toluic acid, and p-tert-butylphenol in t-butylmethyl ether •Extract p-toluic acid from the ether layer with NaHCO3 solution •Extract p-tert-butylphenol from the ether layer with NaOH
In this lab you will use a method called visible spectroscopy to determine the concentration of a solution of CoCl2. This method relies on the fact that colored solutions will
Magic marker inks are often mixtures of several compounds. Paper chromatography is a common method of separating various components of a mixture. After separation, you can observe the different colors that make up a particular color of magic marker ink. You can also calculate a ratio Rf, which compares how far each compound traveled to how far each solvent (substance that dissolves another substance) traveled during the experiment. Rf = Ds/Df Ds = Distance traveled by the compound Df = Distance traveled by the solvent Materials: coffee filter, tape, isopropyl alcohol (rubbing alcohol), water, 3 different color magic markers (not permanent); 3 identical tall, narrow drinking glasses; metric ruler, 3 pencils Pre-lab Questions: List one extensive and one intensive property of marker ink.
The test for Sodium Bicarbonate included mixing that with HCl. After doing this experiment bubbles would form in the solution. This was CO2 being released. This reaction is a way of testing for Sodium Bicarbonate. BACKGROUND: For these experiments a 96-well plate was used.
Esterfication Abstract: Through the process of esterification, carboxylic acid was reacted with an alcohol in order to produce an ester and water as the products. An acid called benzoic acid was reacted with an alcohol identified as ethanol. Through the use of heat and a catalyst, which in this case was sulphuric acid, an ester in the form of ethyl benzoate was produced along with water. The cherry odour comes from the ester called ethyl benzoate. Theory: The purpose of this lab is to achieve a specific odour through the process of esterification where carboxylic acid and alcohol react to produce an ester and water with the assistance of heat and a catalyst such as sulphuric acid.
This technique prevents the product to contact other reactants, and leave the heating environment which might cause side reactions. The removal of the product also helps to shift the equilibrium position of the incomplete reaction to the right hand side, and prevents backwards reaction, resulting in an increased yield of products. This experiment also introduces the idea of azeotrope. An azeotrope is a mixture of two or more pure compounds in such a ratio that its composition cannot be changed by simple distillation. This is because when an azeotrope is boiled, the resulting vapour has the same ratio of constituents as the original mixture of liquids.
The chemical method uses selective separation. By knowing the quantity of each component in a mixture gives one the ability to readily duplicate mixture at will. Therefore the procedure will need dutiful analyzing and documentation. Procedure: The mixing of the three components SiO2 (s), NaCl (s) and CaCO3 (s ) with water produced a white milky substance which was then filtered leaving SiO2 (s), and