Symptoms of the disease include abnormal involuntary movements, a severe decline in thinking and reasoning skills, irritability, depression and mood changes. The gene defect causes abnormalities in the brain protein that leads to
Biology Research Paper Duchenne Disorder (Duchenne Muscular Dystrophy) Duchenne disorder is classified as a very severe, rare case of muscular dystrophy, which is a group of inherited disorders that cause muscle weakness. It affects all voluntary muscles, as well as the heart and breathing muscles. This particular disease is, in fact, genetic. Unlike a lot of genetic disorders, Duchenne disorder occurs in people that do not have a family history of the condition. According to a study by the Muscular Dystrophy Campaign, in the United Kingdom, 1 of every 3500 males is born with Duchenne disorder.
Severe Rheumatoid Arthritis is a crippling condition that often prevents people from working within five to ten years of diagnosis. Osteoarthritis Osteoarthritis is a type of arthritis that is characterized by a gradual loss of cartilage in the joints. Cartilage is tough tissue that provides cushioning between the bones that make up the joints. Loss of this protective cushion often results in bone spurs and cysts and allows bones to rub on each other, which is extremely painful. The affected joints are usually “load-bearing” joints located in the knees, hands, hips, feet, and spine, although the condition often starts in a single joint.
When discovered, these remnants of corrupted brain cells are the primary method today in identifying Alzheimer's disease. Granulovacuolar degeneration is when fluid filled vacuoles are evident in the cells of the hippocampus. The dendrites and nucleus in the cell disintegrate entirely, lost in the body’s disposal system (Talan, 2011). The brain actually loses mass and shrinks. Eventually so much of the brain has been lost that it can no longer support
Dr. Bethune brought recognition and change to Canada through his advancements and dedication in medicine. Specifically, during the Spanish Civil War in 1936, he organized a mobile blood bank to be setup on the front lines of the war. Soon after, Bethune and his team were completing over 1000 blood transfusions a day. “His mobile blood bank is considered the greatest medical innovation from the war.” (macleans.ca). In essence, the mobile blood bank revolutionized medicine and brought recognition to Canada by providing a more immediate and accessible help to the wounded.
Loss of SMN1 gene results in loss of function of specific proteins required for RNA processing. This abnormal RNA processing seems to have a toxic effect on the lower motor neurons and results in their progressive degeneration in the spinal cord and also in the brainstem motor nuclei of cranial nerves 5,7,9 and 12. Werdnig-Hoffman paralysis or SMA type I can also be related to / can also cause congenital heart defects in severe cases. Studies have shown that patients with a single SMN2 copy, have higher incidence of getting an atrial septal defect (ASD) or ventricular septal defect (VSD). Patients with only 2 copies of SMN2, have higher incidence of getting minor cardiac anomalies including patent foramen ovale (PFO) and patent ductus arteriosus (PDA).
Congestive Heart Failure (CHF) Congestive Heart Failure or CHF is a severe circulatory congestion due to decreased myocardial contractility, which results in the heart’s inability to pump sufficient blood to meet the body’s needs. In general, causes can be classified according to the following: a. Volume overload may cause the right ventricle to hypertrophy to compensate for added volume. b. Pressure overload usually results from an obstructive lesion, such as COA c. Decrease contractility can result from problems such as sever anemia, asphyxia, heart block and acidemia.
When this happens, the muscles and tissues that surround the joint weaken. This can deform your joint and make it hard for you to move. Rheumatoid arthritis is an autoimmune disease in which the body's immune system attacks itself. The pattern of joints affected is usually symmetrical, involves the hands and other joints and is worse in the morning. Rheumatoid arthritis is also a systemic disease, involving other body organs, whereas osteoarthritis is limited to the joints.
Outline: Support 1: Muscular Dystrophy is a disease that weakens the muscles that move the body. I: some appear in infancy or childhood. II: same may not appear until middle age. Support 2: Muscular Dystrophy type can very in whom they affect. I: type of Muscular Dystrophy.
With Becker disease people often experience temporary attacks of muscle weakness, normally in the arms and hands, this is normally brought on by movement after periods of rest. They may also develop mild, permanent muscle weaken over a period of time. This is not shown in people with Thomsen disease. Although myotonia can affect any skeletal muscles, including muscles of the face and tongue, it occurs most often in the legs. Myotonia causes muscle stiffness that can interfere with movement.