Crohn’s disease is an ongoing inflammation bowel disease of the digestive tract, also referred to as the gastrointestinal (GI) tract that can cause ulcerations which is breaks in the lining of the small and large intestines. Crohn’s disease is named after the physician who described the disease in 1932 (www.gicare.com). Crohn’s disease can affect any area of the GI tract, from the mouth to the anus, but it most commonly affects the lower part of the small intestine, called the ileum. The swelling extends deep into the lining of the affected organ. The swelling can cause pain and can make the intestines empty frequently, resulting in diarrhea.
What functions will be compromised if the ulcer eats through the submucosa and then the muscularis? Absorption would not happen correctly some of the ingested and secreted may seep out of the lumen. This also could create a pathway of entry for pathogens if the ulcer ate through to the muscularis mucosa and also lose some control of defecation. (Jenkins & Tortora pg. 825,826) B.
Ulcerative Proctitis which means the inflammation is just in the rectum; and Proctosigmoiditis which involves the rectum and sigmoid colon which is the lower end of the intestine. There is also Left-sided colitis, which involves the rectum, sigmoid and descending colon; Pancolitis affects the entire colon and Fulminant colitis is a rare and severe form of UC which can be life-threating and affects the entire
During the active phase the most common signs and symptoms include diarrhea, abdominal cramping, rectal bleeding, ulcers, reduced appetite, and weight loss. Other signs and symptoms include fever, fatigue, arthritis, eye inflammation, skin disorders and inflammation of liver or bile ducts. Diarrhea is the most common symptom due to the inflammation of the intestines that causes them to secrete a large amount of fluid and salt. Since the colon cannot absorb this extra fluid, the person develops severe diarrhea. Abdominal pain and abdominal cramping is caused the inflammation of the walls and eventually thickens the walls with scar tissue and leads to cramping.
Systemic Lupus Erythematosus Anatomy & Physiology Immune System Systemic lupus erythematosus (SLE) or also called Lupus is an autoimmune disorder. Which means that the body’s immune system mistakenly attacks healthy tissue, it may affect the skin, joints, kidneys, brain, and other very important organs. This ultimately leads to chronic (long-term) inflammation. The severity of the disease varies, from mild cases only involving the skin to severe cases affecting multiple organs, including the brain. Lupus sufferers experience flares or intervals of active disease and
Instead of acting as a lubricant, the secretions plug up tubes, ducts and passageways, especially in the lungs and pancreas. (Retrieved from mayo clinic). The thick and sticky mucus can cause the lungs to clog and lead to life-threatening lung infections. In addition it can obstruct the pancreas and stop natural enzymes from helping the body break down and absorb food properly. In addition,
Crohn’s Disease Rosa Capela Kaplan University: SC131 January 21, 2015 What is Crohn’s Disease? Crohn’s Disease is an inflammatory bowel disease, causing the lining of your digestive tract to flame up. When the disease is active many symptoms can be caused, including abdominal pain, severe diarrhea, fatigue (extreme tiredness), weight loss, and malnutrition (lack of proper nutrition). Inflammation of the skin eyes and joints, inflammation of the liver of bile ducts and delayed growth or sexual development, in children are also signs and symptoms of Crohn’s Disease. Scientists believe Crohn’s Disease is caused by a combination of these 3 factors: Immune system problems, genetics, and environmental factors.
Crohn’s Disease Inflammatory Bowel Disease (IBD) includes many categories, but two particular illnesses are Ulcerative Colitis and, a more severe, Crohn’s Disease. The more commonly known disease, Crohns, is seriously unacknowledged in the severity except by doctors and patients with Crohns. Crohn’s disease is a growing problem in humanity. Crohn’s is a painful, incurable, lifelong disease that can affect anyone; although, Crohns is not usually terminal if identified and properly addressed. By definition, “Crohn’s disease is a chronic (ongoing) disorder that causes inflammation of the digestive or gastrointestinal (GI) tract.
Some of the common triggers for sickle cell crisis are fever, dehydration, stress, infection, hypoxia, bleeding, cold exposure, and drug and alcohol use. The immune system for people with sickle cell anemia is weakened which increases the likelihood of infection from flu viruses and bacteria which could lead to a fever. There are four different types of crises that are label based on the area of the body affected. They are bone, abdominal, chest, and joint crisis. During a sickle cell crisis, the pregnant person may present with severe unrelenting pain that is accompanied by nausea, vomiting, coughing up blood, diarrhea, or decreased range of motion of the affect extremity.
Crohn's and a related disease, ulcerative colitis, are the two main disease categories that belong to a larger group of illnesses called inflammatory bowel disease (IBD) (Crohn's & Collitis Foundation of America, 2011). While the exact cause of Crohn's disease is unknown, the condition is linked to a problem with the body's immune system response. The inflammation caused by Crohn's disease often spreads deep into the layers of affected bowel tissue. Like ulcerative colitis, another common IBD, Crohn's disease can be both painful and debilitating, and sometimes may lead to life-threatening complications. While there is no known cure for Crohn's disease, therapies can greatly reduce the signs and symptoms of Crohn's disease and even bring about long-term remission.