Cystic Fibrosis Cystic fibrosis (CF) is a non-curable inherited defect of a gene called the cystic fibrosis transmembrane conductance regulator gene (CTFR). The (CTFR) gene makes a protein that regulates the movement of water and salt throughout the cells in our body. This defective gene causes the production of thick, sticky mucus. It builds up and first clogs the small airways, but eventually it can affect all airways. The airways are responsible for carrying harmful bacteria out of the body.
The disease is often detected in the first few weeks of life. Due to the buildup of lipids in the CNS, motor control, swallowing, and mental capabilities are impaired. In the very worst of cases most children do not live beyond two years, in mild cases some are known to live into their teen years. The trait is passed on when both parents carry a defective gene that moderates protein sphingomyelin. The likelihood of the child getting Farber’s is twenty five percent; there is a fifty percent chance that the child will carry the defective gene with no symptoms, a carrier.
If left untreated, a MRSA skin infection can go progressively deeper into the body, infecting blood and organs. Read more: http://www.foxnews.com/health/2012/05/08/mrsa-antibiotic-resistant-bug-that-has-health-officials-worried/#ixzz2UnWmfNeQ When MRSA infects skin, a swollen, red area develops, and it is usually painful. MRSA skin infections may develop pus or weep other fluids. If left untreated, a MRSA skin infection can go progressively deeper into the body, infecting blood and
Pancreatic cancer, also called pancreatic carcinoma, is cancer of the pancreas. The pancreas is an organ located behind the stomach, which makes and releases enzymes that help the body absorb food, especially fats. The pancreas also makes the hormones insulin and glucagon, which help control your blood sugar levels. Pancreatic cancer is a malignant neoplasm originating from transformed cells arising in tissues forming the pancreas. The most common type of pancreatic cancer, accounting for 95% of these tumors, is adenocarcinoma.
This gene codes for a protein that form an ion channel, facilitating the movement of salts (sodium and chloride ions) and water across the cell membrane. This is important in creating sweat, digestive juices and mucus [5]. In patients with cystic fibrosis, CFTR is prevented in carrying out these functions due to alteration of salt and water balance in lungs. This eventually causes dehydration in most of the organs and causes thick, sticky mucus to build up in the lungs and digestive tract. Consequently, this creates an environment that favours bacterial growth, and people who suffer from cystic fibrosis are exposed to rapid respiratory tract infections which lead to inflammation and progressive lung
Sickle Cell Anemia is where the red blood cells become sickle shaped when they are usually supposed to be a round donut shape. The donut shape moves easily through the blood carrying oxygen, where the sickle shape has trouble moving through the blood and can cause problems and pain in the blood vessels. Sickle Cell Anemia is an inherited disease. Each person receives 2 copies of the sickle gene,one from each parent, and this causes abnormal hemoglobin found in sickle cell. Hemoglobin is a protein inside red blood cells which carry oxygen all over the body an gives the blood its red color.
It's believed to be an autoimmune disease, in which the body's immune system attacks its own tissues (mayoclinic.org). There is a fatty substance called myelin that protects the nerves in the brain and spinal cord. In multiple sclerosis the immune system attacks this fatty substance and exposes the nerves. In this process the damage to the nerves causes the
Cystic Fibrosis Cystic fibrosis is a hereditary disease, which is caused by the accumulation of mucus in epithelial cells of the digestive, respiratory, and reproductive tracts. Cystic fibrosis transmembrane conductance regulator (CFTR) facilitates chloride channel and controls several other metabolic pathways. Mutations in the particular gene cause cystic fibrosis. CFTR gene functions in regulating sweat, digestive juices, and mucus. A human body consists of two functioning CFTR gene, and when neither gene functions efficiently, cystic fibrosis is developed, and hence has autosomal recessive inheritance.
Kelly Stewart Week4 Outline on Diabetes Mellitus Pathophysiology MED1210XC Lcheatem Diabetes Mellitus Diabetes Mellitus is a metabolic disease that is characterised with high blood sugar.The level of the sugar in your body because of the deficient insulin that is not produced by the pancrease. Sweet Urine is another problem that is caused by having diabetes, because of high levels of blood glucose leads to spills into the urine that is why they have the hypoglycemic or term reffered as "sweet urine." Diabetes Mellitus was first identified as diabetes, but now their a several different types of diabetes. which has come into play over the years, you have Diabetes Type1 an Type 2, then their is gestational diabetes which happens when you are pregnant. The cause of diabetes is the insufficient production of insulin and the body must have it to regulate the blood sugar.
People who inherit one sickle cell gene and one normal gene have sickle cell trait (SCT). People with SCT usually do not have any of the symptoms of sickle cell disease (SCD), but they can pass the trait on to their children. It is inherited from the parents, there is a 50% chance that a child will inherit the trait, but may not have the disease. People with sickle cell disease (SCD) start to have signs of the disease during the first year of life, usually around 5 months of age. Symptoms and complications of SCD are different for each person and can range from mild to severe.