Biochemistry 208.5 Essay

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 Competency 208.5.1: DNA, RNA A. & B DNA duplication of the leading strands and lagging strands: the lagging strands are broken, with short Okazaki fragments being shaped and connected together. The primase produces the short strands of RNA that fix to the single stranded DNA to recruit the DNA synthesis by DNA polymerase. The helicase opens the double stranded DNA for duplication, making a forked structure known as the replication fork. This enzyme can work on 5; 3; direction so it duplicates the leading stand continuously. The DNA ligase enzyme repairs the single strand breaks into duplex DNA in living organisms using the complimentary strands. The Okazaki fragments are being shaped and connected together to form short double stranded DNA sections. C. In decoding the genetic information of a cell, transcription is the first step. An enzyme called RNA Polymerase, builds RNA molecules that complement a portion of one of the 2 strands of the DNA helix. Messenger RNA brings the instructions for coding, protein synthesis or transcripts to the Ribosomes via tRNA. . This is where the steps of protein synthesis take place. Translation is when the tRNA bring the amino acids to pair with their codons resulting in protein chains. D. Death cap mushrooms belong to a collection of fungi called the amanita haloids and are though to possibly be the most poisonous fungi. Death cap mushrooms cause RNA polymerase inhibition. It does not produce instant indications of poisoning. The poison attacks the liver and kidneys and has no known cure. By inhibiting RNA polymerase the mushroom generates a perfect storm of events uniquely suited to destroying body systems. Without RNA polymerase the body cannot create any RNA thereby eliminating the availability to create new

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