Ativan Essay

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Drug Name (generic/trade) | Lorazepam/Ativan | Drug Class | Anxiolytic; benzodiazepine | Mechanism of Action | Potentiates GABA effects by binding to specific benzodiazepine receptors | Indications | Control anxiety; treat status epilepticus; preoperative sedation | Dosing | Adults PO (divided doses) 2-6 mg/day; max: 10 mg/day IM 0.05 mg/kgIV 0.044 mg/kgChildren PO/IV 0.05 mg/kg q4-8 hours; max: 2 mg per doseOlder adultsPO 0.5 – 1 mg/day; max 2 mg/day | Side Effects | Drowsiness, dizziness, weakness, confusion, blurred vision, nausea, vomiting, anorexia, sleep disturbance, restlessness, hallucinations ADVERSE RXNs: Hypertension, hypotension | Assessment | Assess for contraindications; BZD allergy; impaired liver or kidney function; SI; get Hx of client’s anxiety reaction; determine client’s support system; obtain client’s drug hx; report possible drug-drug interaction. | Nursing Diagnoses (potential) | Anxiety r/t panic.Impaired physical mobility r/t drowsiness, weakness.Risk for injury r/t CNS effects.Disturbed sleep pattern r/t CNS effects.Disturbed thought processes and disturbed sensory perception r/t CNS effects. | Planning/Outcome | Client’s anxiety and stress will be reduced through non-pharmacological methods, anxiolytic drugs as orders, or support/group therapy. | Nursing Interventions | Observe client for side effects; recognize that drug tolerance and dependency can occur.Monitor vital sx, especially BP and pulse; orthostatic hypotension can occur. | Client Teaching | Advise client not to drive or operate dangerous equipment, because sedation is a common side effect.Instruct client not to consume alcohol or other CNS depressants (narcotics) while taking.Teach clients other ways to control excess stress and anxiety (relaxation techniques, long walks, etc.).Encourage client to follow prescribed drug regimen and not to stop abruptly

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