Ap Biology Essay

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Arizona Questions-Metabolism 1. Correct! * Glycolysis leads to the production of ____________ and two molecules of ATP. In the absence of oxygen, fermentation leads to the production of ______________. Glycolysis plus the citric acid cycle can convert the carbons of glucose to _________ , storing the energy as ATP, _____________ and ___________. * B. pyruvate, lactic acid, CO2, NADH, FADH2 2. At the end of glycolysis, each molecule of glucose has yielded 2 molecules of _______, 2 molecules of ________, and a net of 2 molecules of _________. * D. pyruvate; NADH; ATP 3. Trematol is a metabolic poison derived from the white snake root. Cows eating this plant concentrate the poison in their milk. The poison inhibits liver enzymes that convert lactic acid to other compounds for metabolism. Why does physical exertion increase symptoms of poisoning by trematol? Why does the pH of the blood decrease in a person who has digested trematol? * A. Physical exertion would increase the production of latic acid by fermentation, and the build up of lactic acid decreases blood pH when liver enzymes are blocked. 4. Dinitrophenol (DNP) is an uncoupler, or has the ability to separate the flow of electrons and the pumping of H+ ions for ATP synthesis. This means that the energy from electron transfer cannot be used for ATP synthesis. Fifty years ago, DNP was given as a drug to help patients lose weight. Why does this work? Why would this be dangerous? * B. If electron transport doesn't produce ATP, then much more sugar must be metabolized for energy needs. Very low production of ATP would be lethal. 5. If you isolate mitochondria and place them in buffer with a low pH they begin to manufacture ATP. Why? * B. The high external acid concentration causes an increase in H+ in the inter membrane space leading to increased ATP production by ATP

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