Antacid Project Essay

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Indigestion and Titration: An Acid - Base Titration Imagine yourself as the Lead Analytical Chemist at Kaplan Industries. Your first big assignment is to investigate the strength of several commercial antacids for the Food and Drug Administration (FDA). They have sent five antacids to be tested with a back - titration that works as follows: • First, each antacid tablet is mixed with 40 mL of 0.1 M HCl — this acidic solution is the same stuff that is in stomach acid, and one antacid pill is nowhere near enough to neutralize all 40 mL of the acid. • So, to see how m uch extra help each antacid pill needs to neutralize 40 mL of 0.1 M HCL, you add 0.05 M NaOH drop - by - drop to back - titrate the solution until the pH is neutral. • What this means is that, the stronger the antacid tablet, the less NaOH it will take to help br ing the acid to neutral. (In other words, the stronger antacid tablets counteract more of the original HCl, leaving the solution closer to neutral before the NaOH is added.) Here are your results: Maalox Tums Mylanta CVS brand Rennies Mass of one dose antacid 20.0 g 21.0 g 18.0 g 18.3 g 17.5 g mL NaOH used in back - titration 24.1 mL 22.4 mL 20.0 mL 19.9 mL 24.4 mL 1. Which is the strongest antacid, on a single - dose basis? Which is the weakest? Explain and show your calculations. 2. Which are the strongest and weakest, on a by - weight (mass) basis? 3. When people do back titrations, they usually watch the solution for a color change when the solution becomes neutral. What might you have used in the above experiment to get this color chan ge to happen in the solution? At what pH would the solution have been neutral? 4. If you had walked into the lab, only to discover that you only had 0.1 M sulfuric acid available to run your tests, how might this have affected your

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