The earliest precursor of pollution generated by life forms would have been a natural function of their existence. The attendant consequences on viability and population levels fell within the sphere of natural selection. These would have included the demise of a population locally or ultimately, species extinction. Processes that were untenable would have resulted in a new balance brought about by changes and adaptations. At the extremes, for any form of life, consideration of pollution is superseded by that of survival.
For humankind, the factor of technology is a distinguishing and critical consideration, both as an enabler and an additional source of byproducts. Short of survival, human concerns include the range from quality of life to health hazards. Since science holds experimental demonstration to be definitive, modern treatment of toxicity or environmental harm involves defining a level at which an effect is observable. Common examples of fields where practical measurement is crucial include automobile emissions control, industrial exposure (e.g. Occupational Safety and Health Administration (OSHA) PELs), toxicology (e.g. LD50), and medicine (e.g. medication and radiation doses).
"The solution to pollution is dilution", is a dictum which summarizes a traditional approach to pollution management whereby sufficiently diluted pollution is not harmful. It is well-suited to some other modern, locally scoped applications such as laboratory safety procedure and hazardous material release emergency management. But it assumes that the dilutant is in virtually unlimited supply for the application or that resulting dilutions are acceptable in all cases.
Such simple treatment for environmental pollution on a wider scale might have had greater merit in earlier centuries when physical survival was often the highest imperative, human population and densities were lower, technologies were simpler and their byproducts more benign. But these are...