In the experiment, toluene was alkylated with 2-chloropropane to synthesize isomers of isopropyltoluene in 47% yield, weighing 2.66g. The final product had a purity of 91.8% while the appearance was a colourless clear liquid with a strong odour. The results suggest that although the product yield was low, the experimental design led to the production of isopropyltoluene in high purity. REFERENCES 1. Smith R, McKee J, Zanger M. The electrophilic bromination of toluene: Determination of the ortho, meta, and para ratios by quantitative FTIR spectrometry.
pyridinium hydrobromide perbromide type of stationary phase column length column temperature rate flow of the carrier gas List the 4 general factors that affect the separation obtained on a gas chromatograph What specific technique is used to collect/isolate your purified unknown compound at the end of the recrystallization experiment? suction filtration 14 of 22 4/16/12 9:15 PM StudyBlue Flashcard Printing of Lab Final 2211L UGA
3. Solid iodine in 1 mL of alcohol is slightly more soluble. Residue still remains on the bottom and alcohol changed to an orange red color. 4. Solid iodine in 1 mL of mineral oil is slightly soluble.
Samantha Monette Lab Section E Wednesday 10:00-12:50 p.m. Bromination/Debromination of Cholesterol Abstract: The purpose of this experiment was to purify commercial cholesterol. The commercial cholesterol was brominated using bromine as the reagent. After the compound was cooled and vacuum filtrated, dibromocholesterol was obtained. To purify the dibromocholesterol, zinc was added as the reagent. After a series of washes to remove any impurities, the compound was dried and decanted, cholesterol was synthesized.
Acetanilide is also used as an intermediate for the synthesis of rubber accelerators, dyes, and is used as a precursor in penicillin synthesis. The melting point of the base was determined to be between 80-87 degrees. Based on the melting point we identified the identity of our base as Ethy-4-amiobenzoate. Ethy-4-amiobenzoate is an anesthetic which is applied topically to the skin and mucous membrane and is also used to suppress the gag reflex in various
Experiment 5: Preparation of Cyclohexene- Acid Catalyzed Elimination of Cyclohexanol Ball State University Organic Chemistry Lab 231 (Sec. 5) Dr. Bock/Daniel Miller Tiffany Raber 5 November 2012 Purpose: To prepare an alkene by an elimination reaction of an alcohol in the presence of sulfuric acid as a catalyst to produce a successful yield and desired results for the purity of the alkene. Introduction: The dehydration of an alcohol such as cyclohexanol is a useful technique for generating alkenes. The success of this reaction relies on a dehydration, such as the presence of a strong acid (sulfuric acid). Because this reaction is reversible, a fractional distillation is necessary to produce cyclohexene, water, and some impurities and a simple distillation is followed to further purify the product.
Synthesis and Analysis of Cholesterol by Bromination and Debromination of Commercial Cholesterol with Physical, Chemical, and Chromatographic Techniques The purpose of this experiment was to purify commercial grade cholesterol from impurities using organic reactions. Bromination of cholesterol yielded a product with a significantly different structure that was more easily separated from unwanted cholesterol derivatives. This reaction was reversed by debromination which yielded cholesterol now largely free of impurities. Commercial cholesterol was dissolved in t-butylmethyl ether, a bromine mixture was added, and an electrophilic addition reaction proceeded. This product, dibromocholesterol, was washed and debrominated by an elimination reaction using zinc dust.
Title: Bromination of (E) – Stilbene (Microscale Procedure) Author’s Name: Reinaldo George Professor: Elvis Barrett Date of Experiment: Thursday July 16th 2015 Institution: Nova Southeastern University Abstract The purpose of this experiment was to synthesize the second intermediate in the b series of Sequential Reactions by carrying out the bromination of (E)-stilbene to obtain meso-stilbene dibromide. This product is the precursor to diphenylacetylene, the next synthetic intermediate in the b series. A further purpose of this experiment is to demonstrate the stereospecific addition of bromine to alkenes. The percentage recovery was also calculated and recorded. On completion of this experiment; my lab partners and I were able to successfully synthesize the second intermediate in the b series of the
Chromatography: Separating Mixtures Introduction: Magic marker inks are often mixtures of several compounds. Paper chromatography is a common method of separating various components of a mixture. After separation, you can observe the different colors that make up a particular color of magic marker ink. You can also calculate a ratio Rf, which compares how far each compound traveled to how far each solvent (substance that dissolves another substance) traveled during the experiment. Rf = Ds/Df Ds = Distance traveled by the compound Df = Distance traveled by the solvent Materials: coffee filter, tape, rubbing alcohol, water, 3 different color magic markers (not permanent); 3 identical tall, narrow drinking glasses; metric ruler, 3 pencils Pre-lab Questions: 1.
Observations of Chemical Changes Purpose: To examine the reactions of chemicals and see what types of changes can occur. Procedure: I used a 96-well plate and the following chemicals to document the chemical changes that occur: Ammonia, Bromthymol Blue, Copper (II) Sulfate, FDC Blue dye #-1, Hydrochloric Acid, Lead (II) Nitrate, Phenolphthalein Solution, Silver Nitrate, Sodium Bicarbonate, Sodium Hydroxide, Sodium Hypochlorite, and Starch Solution. Data Tables: Well #/Question | Chemicals | Reaction | A | NaHCO3 and HCl – CO2 | Bubbles formed | B | HCl and BTB | Turns a yellow/orange color | C | NH3 and BTB | Turned to orange | D | HCl and Blue Dye | Turns green | E | Blue Dye and NaOCL | Stayed blue | F | Kl and Pb(NO3)2 |