Andes Virus Essay

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Andes Virus

The Andes virus is one of five Hantaviruses known to cause Hantavirus Pulmonary Syndrome.   Hantavirus Pulmonary Syndrome begins as nonspecific feverish symptoms, sharing many of its initial symptoms with other more common viral infections. Patients then quickly develop non-cardiogenic pulmonary edema, respiratory failure, and shock. The overall case fatality rate of HPS is approximately 40 percent.
      Christina Spiropoulou from Journal of Virology gave some insight about Andes Virus and some keys factors of how it adheres to its host.
      “There are high levels of virus replication that occur in micro-vascular endothelial cells but without a virus-induced cytopathic effect. However, virus infection results in micro-vascular leakage, which is the hallmark of these diseases. VE-cadherin is a major component of adherens junctions, and its interaction with the vascular endothelial growth factor (VEGF) receptor, VEGF-R2, is important for maintaining the integrity of the endothelial barrier.” ( Journal of Virology)
      The Andes Virus has been said to be more deadly than Anthrax. In some cases, I can see this to be true. In the movie “Alien Invaders”, the Andes virus infected a small town very quickly. Within hours/days people who were subjected to such turmoil laid dead from this fast acting virus. The Andes virus is derived from rodent feces and decomposition occurs, when disturbed, it becomes air-borne infecting anyone who dares to take a breath while in its path. The rodents are considered life long carriers that are not affected by the virus. As watched in the video, the doctor of this small town was quite baffled of what the virus was at first because it was never discovered before that the Andes virus could be contagious and infect humans the way that it has. One epidemiologist was flown in by plane to prepare an investigation to narrow the possibilities of where such a virus derived from. When he had no luck for days from the traps he...

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