An Account of the Immune Response to Parasites

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Gabriella Wright BSc Biomedical Science Y2 Immunology An account of the immune response to parasites Introduction As a host the human body is constantly bombarded by pathogenic invasion. The prime first defence to these invasive antigens is our skins epithelial surface and gut lining. The Innate and adaptive immune system work together to provide the host with a unique defence system, in encountering a wide variety of pathogens. There are four types of pathogen that can invade a host; these are viruses, protozoa, helminths and bacteria. The following essay will give an account of the immune response to bacterial parasites, and then follow with an account of an immune response to Malaria which is a protozoan disease. Extracellular and intracellular bacteria and the immune response A parasite is an organism that can live symbiotically with other organisms or use the organism to provide it with nutrients so it can multiply until the organism dies, it will then without any conscious feelings move on and live inside another host. Parasites are bacteria, viruses, protozoa, and also animals, e.g. worms and arthropods. The host’s defence to bacterial infection is acquired by specialised cells releasing an antibody that will recognise the bacteria and destroy it by phagocytosis, this happens all the time unknown to the human host, unless an invading parasite is virulent enough to cause a conscious reaction in the host. Bacteria enter the human body in a number of ways, either through the skin surfaces that have been damaged e.g. cuts, abscesses, recent surgery or via a more natural route e.g. gastrointestinal tract, genitourinary tract and respiratory system, the innate immune system can take care of low grade bacteria that’s small in size by non-specific defences, whereas the adaptive immune system come into play when a bacteria is larger in

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