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This medicine can increase your risk of life-threatening heart or circulation problems, including heart attack or stroke. This risk will increase the longer you use Advil. Do not use this medicine just before or after having heart bypass surgery (also called coronary artery graft, or CABG).

Seek emergency medical help if you have symptoms of heart or circulation problems, such as chest pain, weakness, shortness of breath, slurred speech, or problems with vision or balance.

This medicine can also increase your risk of serious effects on the stomach or intestines, including bleeding or perforation (forming of a hole). These conditions can be fatal and gastrointestinal effects can occur without warning at any time while you are taking Advil. Older adults may have an even greater risk of these serious gastrointestinal side effects.

Call your doctor at once if you have symptoms of bleeding in your stomach or intestines. This includes black, bloody, or tarry stools, or coughing up blood or vomit that looks like coffee grounds.

Do not take more of this medication than is recommended. An overdose of Advil can cause damage to your stomach or intestines. The maximum amount of Advil for adults is 800 milligrams per dose or 3200 mg per day (4 maximum doses). Use only the smallest amount of Advil needed to get relief from your pain, swelling, or fever. Avoid taking Advil if you are taking aspirin to prevent stroke or heart attack. Advil can make aspirin less effective in protecting your heart and blood vessels. If you must use both medications, take the Advil at least 8 hours before or 30 minutes after you take the aspirin (non-enteric coated form). Do not drink alcohol while taking Advil. Alcohol can increase your risk of stomach bleeding caused by Advil.
What is Advil?
Advil is in a group of drugs called nonsteroidal anti-inflammatory drugs (NSAIDs). Advil works by reducing hormones that cause...