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Williams, Craig A.. "Oxygen Uptake Kinetcs During Treadmill Running in Boys and Men." Journal of Applied Physiology 90(2001): 1700-1706.

The purpose of this study was to compare the kinetics of the oxygen uptake (VO2) response of boys to men during treadmill running using a three-phase exponential modeling procedure. Eight boys [age: 12 ± 0.2 (SD) yr, body mass: 43.5 ± 6.8 kg] and eight men (age: 30 ± 7.3 yr, body mass: 75.0 ± 5.9 kg) volunteered to participate in the study. The subjects were instructed to arrive at the laboratory in a rested and fully hydrated state, at least 3 h postprandial (after a meal), and to avoid strenuous exercise in the 48 h preceding a test session. Subjects wore the same running shoes and lightweight running kit for all tests. For each subject, tests took place at the same time of day (±2 h) to minimize the effects of daily biological variation on the results.
The subjects were required to visit the laboratory on four occasions. The first visit was used to determine the LT (Lactate Threshold) and the VO2 max. During the remaining sessions, the subjects performed two to four repetitions of square-wave transitions from rest to one of two exercise intensities: 80% LT and 50% of the difference in VO2 between LT and VO2 max. On a given day, a subject would complete two or three transitions of the same exercise intensity. The transitions were separated by 1 h of recovery. The transitions performed on a given day were determined at random, and the study was completed within 2 weeks for all subjects.
All tests were performed on a motorized treadmill with the grade set at 1%. During the exercise tests, pulmonary gas exchange was determined breath by breath. Subjects breathed through a low-dead-space (90 ml), low-resistance (0.65 mmH2O • l 1 • s at 8 l/s) mouthpiece and turbine assembly. Heart rate was recorded telemetrically throughout the exercise tests.
Subjects performed incremental exercise to...